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The dorsal cochlear nucleus (DCN, also known as the "tuberculum acusticum"), is a cortex-like structure on the dorso-lateral surface of the brainstem. Along with the ventral cochlear nucleus (VCN), it forms the cochlear nucleus (CN), where all auditory nerve fibers from the cochlea form their first synapses. ==Anatomy== The DCN differs from the ventral portion of the CN as it not only projects to the central nucleus (a subdivision) of the inferior colliculus (CIC), but also receives efferent innervation from the auditory cortex, superior olivary complex and the inferior colliculus. The cytoarchitecture and neurochemistry of the DCN is similar to that of the cerebellum, a concept that currently is important in theories of DCN function.〔Bell CC, Han V et al. Cerebellum-like structures and their implications for cerebellar function. Annu.Rev.Neurosci. 2008.Vol31.PMID 18275284〕 Thus, the DCN is thought to be involved with more complex auditory processing, rather than merely transferring information. The pyramidal cells or giant cells are a major cell grouping of the DCN. These cells are the target of two different input systems. The first system arises from the auditory nerve, and carries acoustic information. The second set of inputs is relayed through a set of small granule cells in the cochlear nucleus. There are also a great number of neighbouring cartwheel cells.〔Wouterlood FG and Mugnaini E. Cartwheel neurons of the dorsal cochlear nucleus: a Golgi-electron microscopic study in rat. J.Comp Neurol 1984 Jul20;227(1) PMID 6088594〕 The granule cells in turn are the target of a number of different inputs, including both those involved in auditory processing and, at least in lower mammals, somatosensory inputs associated with the head, the ear, and the jaw. Projections from DCN principal cells form the dorsal acoustic stria, which ultimately terminate in the CIC. This projection overlaps with that of the lateral superior olive (LSO) in a well-defined manner,〔Oliver, D. L., G. E. Beckius, et al. (1997). "Simultaneous anterograde labeling of axonal layers from lateral superior olive and dorsal cochlear nucleus in the inferior colliculus of cat." ''J Comp Neurol'' 382(2): 215-29.〕 where they form the primary excitatory input for ICC type O units〔Davis, K. A. (2002). "Evidence of a functionally segregated pathway from dorsal cochlear nucleus to inferior colliculus." J Neurophysiol 87(4): 1824-35.〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Dorsal cochlear nucleus」の詳細全文を読む スポンサード リンク
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